To clarify the colorectal cancer cell potential to secrete these two adipokines, we looked for resistin and visfatin mRNAs and proteins in HCT-116 cell line which is the epithelial cell derived from colorectal adenocarcinoma tissue and positive for TGF-β1 and TGF-β2 expression and has also a mutation in codon 13 of the ras protooncogene. Here, NAMPT is linked to colorectal cancer.