The podoplanin expression is upregulated in many different human cancers, including squamous cell carcinomas of the oral cavity, lung, cervix, esophagus, skin and also in dysgerminomas of the ovary and granulosa cell tumors, breast tumors, colorectal tumors, melanomas, mesotheliomas, and some tumors of the central nervous system (CNS) (8-16). Here, PDPN is linked to cancer.