On the other hand, in our study the increase of podoplanin expression was found higher in supraglottic carcinomas than in glottic carcinomas, although the increase of podoplanin expression was obtained in early stages in patients with supraglottic carcinomas (%35) rather than in patients with glottic carcinomas (%53.8). The gene discussed is PDPN; the disease is glottis carcinoma.