MAPK8IP2 and kidney cancer: According to Dr. Carcinci's article and due to PKM2 and MAPK8IP2 genes mutations report in esophagus, breast and kidney cancers (24, 26, 27) and availability of the genes studying's kit, genetic study for evaluation of PKM2 and MAPK8IP2 polymorphisms in Ameloblastic carcinoma was performed in our study.