Huang et al. (117) have found that aberrant SOX4 expression is correlated with shorter patient survival time and is also related to microsatellite instability and the repression of mutL homolog 1 (MLH1) via DNA hypermethylation, suggesting that miR-129-2 contributes to endometrial cancer by deactivating DNA repair systems. This evidence concerns the gene MLH1 and endometrial cancer.