Moreover, there was an abnormal population of CD5+ and CD23+ small monoclonal B-cells congruous with CLL as well as a population of large neoplastic cells that were CD20+, CD79a+, PAX-5+, CD5−, CD23−, CD30+, CD15−, CD45−, and EBV-encoded RNA (EBER) positive (Figure 3). Here, FCER2 is linked to B-cell chronic lymphocytic leukemia.