Similar to the positive control IFN-γ, which is a known inducer of leishmanicidal activity in human mononuclear phagocytes [49], [50], DAC N-055 at concentrations of 40 to 400 μM that were non-toxic for the monocytes lowered the infection rate and blocked the replication of intracellular L. tropica parasites (Fig. 7B). The gene discussed is IFNG; the disease is infection.