Univariate survival (log-rank test) analysis showed that the overall survival rate for NPC patients with positive expression of p-Mnk1 and p-eIF4E was much lower than that for NPC with negative p-Mnk1 and p-eIF4E expression (p<0.001 and p = 0.004, respectively). Here, EIF4E is linked to nasopharyngeal carcinoma.