The positive percentage of p-Mnk1 and p-eIF4E expression in the NPC and non-cancerous nasopharyngeal epithelium was 83.5% (227/272), 75.4% (205/272), 40.0% (34/85) and 32.9% (28/85), respectively. The gene discussed is EIF4E; the disease is nasopharyngeal carcinoma.