Platelets from healthy control individuals and SCA individuals (CON PLTs and SCA PLTs, respectively) were incubated in culture medium for 4 h at 37°C and the productions of the cytokines, IL-1β, platelet factor 4 (PF4) and IL-8 (Figure 1A–C) were determined by ELISA. This evidence concerns the gene PF4 and autosomal dominant cerebellar ataxia.