SYP and neuroendocrine carcinoma: In contrast to HCT116 that served again as control, transcripts for neuroendocrine markers such as chromogranin A (CGA), neuron specific enolase (NSE), synaptophysin (SYN), vesicular monoamine transporter 1 or 2 (VMAT1; VMAT2), cluster of differentiation 56 (CD56) and gene product 9.5 (PGP9.5) were expressed in NEC-DUE1 (Figure 4 A).