Although it remains to be determined if these cell subsets denominated as DCs and macrophages represent true lineage subsets with distinct transcriptional profiles, we here have adopted and refined the gating strategy applied by Choi et al. and others and used the term DCs when describing cells that express CD11c, and macrophages for CD11c− cells [6], [10], [12], [13]; we have characterized and quantified these cell subsets in C57BL/6 mice and atherosclerosis-prone mice fed a high fat diet. Here, ITGAX is linked to atherosclerosis.