GSK3B and central nervous system cancer: GSK3β activity also appears to be important for leukemic cell growth, as the inhibition of GSK3β led to an induction of apoptosis in leukemic cells and also showed that GSK3β has proapoptotic role in lung cancer by downregulating Survivin activity [17], whereas GSK3beta kinase inhibition in glioma cells induces proapoptotic affect [18, 19].