Specificities of these associations were demonstrated by their significant reduction, ∼77%, 100%, and 95%, respectively, in CIB1 knockdown cells as well as by ∼50%, 72%, and 40%, respectively, in infection with heparin-treated KSHV (Fig. 12.A, lanes 4 and 5 in panels b, c and d). This evidence concerns the gene CIB1 and infection.