Analyzing paraffin-embedded samples, Sousa and colleagues found a variety of proteins overexpressed in metaplasia and intestinal type cancer: lactotransferrin (LTF) and deleted in malignant brain tumor 1 (DMBT1) were validated as metaplasia biomarkers as well as potential prognostic gastric cancer biomarkers [192]. The gene discussed is DMBT1; the disease is gastric cancer.