Small HDL content differed significantly between the groups, with the GCK-MODY group shown to have lower levels of this subfraction from the control (p = 0.0096), T1DM (p = 0.0193) and HNF1A-MODY groups (p = 0.0057) (Fig. 1b). This evidence concerns the gene GCK and type 1 diabetes mellitus.