These include disruptions of KIDINS220, a functional mediator of multiple receptor signalling pathways and essential for cortical development [25, 26]; CHIC2, frequently deleted/rearranged in myeloid malignancies [27]; and KCND2, encoding a potassium voltage-gated channel, which is expressed in both neuronal and glial cells and has been shown to regulate ERK signalling in ganglioglioma [28]. Here, CHIC2 is linked to myeloid neoplasm.