N-3 and n-6 PUFAs in vivo can influence breast tumor cell growth by simultaneously competing for the same metabolic pathway (COX and LOX pathway) to change the balance of tissue eicosanoids, the transcription mediated by nuclear factor κB (NF-κB), and signal transduction mediated by the mammalian target of rapamycin (mTOR) etc.[7-9]. Here, MTOR is linked to breast neoplasm.