CYP2C19 and metabolic syndrome: Using general linear model analysis, we found that differences on the MetS score between subjects with GG genotype and GA + AA genotype on the CYP2C19 rs4244285 remain significant after adjustment for age, gender, smoking status, excessive alcohol consumption and physical inactivity (Mean difference: 0.847; 95%CI: 0.163-1.531; P = 0.015).