FADS1 and metabolic syndrome: Also, recent gene and genome-wide association studies (GWAS) in humans have highlighted the influence of variations in the FADS1 and FADS2 gene cluster on lipid metabolism, glucose metabolism, and other quantitative traits such as total cholesterol and low-density lipoprotein [24-26], and disease conditions such as development of metabolic syndrome [27], coronary artery disease [28], myocardial infarction [29], and dyslipidemia [30].