HSF2 and inflammatory bowel disease: Over the last years evidence has accumulated that HSF1and HSPs are very important for the repair of colonic mucosa epithelium in inflammatory bowel disease and they suppress proinflammatory genes relevant to its pathogenesis [19]–[22], but little is known about the function of HSF2 in the pathogenesis of UC, most studies on HSF2 have been on protein misfolding diseases, delaying aging, development of embryo and sperm [23]–[25].