In the final multivariate models, the adjusted OR (95% CI) for MS across IgM quartiles were 1.00 (reference), 1.09 (0.92, 1.29), 1.07 (0.90, 1.26), and 1.19 (1.002, 1.41) (P for trend  = 0.07), respectively. The gene discussed is CD40LG; the disease is myeloid sarcoma.