IRAK1 and diffuse large B-cell lymphoma: In three MYD88WT-expressing DLBCL cell lines used as a control, neither baseline MYD88/IRAK/TRAF6 complex formation nor constitutive downstream TAK1 phosphorylation was detected, suggesting that MYD88L265P but not MYD88WT is associated with constitutive activation of intracellular signaling through TAK1.