No change in Clarithromycin [62] or Telithromycin [63] metabolism via CYP3A was observed following Uranyl nitrate-induced AKI in rats, whereas decreased metabolism of Etoposide [64] and Losartan [65] metabolism via the CYP3A enzyme was demonstrated following Uranyl nitrate-induced AKI in rats. The gene discussed is CYP3A4; the disease is acute kidney injury.