BIRC5 and cancer: As noted above, significantly high expression of survivin has been reported in many cancers including lung, colon, breast, prostate, bladder, breast, laryngeal, uterine, hepatocellular, soft tissue sarcomas, renal, pancreas, high-grade lymphomas, neuroblastomas, and gastric cancers, as well as in hematologic cancers, such as myelodysplastic syndrome and acute leukemias [53–56,75].