In contrast to wild-type (WT) IAV, infection with a virus deficient in M2 (V7-T9; named here ΔM2) due to mutation of the M2 splice donor site (Hutchinson et al., 2008; Wise et al., 2012) did not relocalize LC3 to the plasma membrane or induce its perinuclear accumulation (Figure 2B). The gene discussed is MAP1LC3A; the disease is infection.