MTOR and neoplasm: To investigate further what ΔT1 reflects about the tumour biology, we have compared ΔT1 with magnetic resonance spectroscopy (MRS) markers of proliferation and apoptosis in vivo[10], as well as histology and immunohistochemistry ex vivo following treatment with the allosteric mTOR inhibitor, everolimus (Afinitor) in two different murine tumour models, RIF-1 and B16/BL6.