There were significantly more CD163 immunoreactive microglia in the brains of Alzheimer patients; frontal cortex (Mann Whitney U?=?105.00, p < 0.001), CA1 (U?=?135.00, p < 0.005), CA3 (U?=?190.50, p < 0.05), CA4 (U?=?177.00, p < 0.05), subiculum (U?=?94.00, p < 0.001) and entorhinal cortex (U?=?141.00, p < 0.005) compared to those from Parkinson patients. Here, CD163 is linked to Parkinson disease.