Sorafenib (SO) is an oral multikinase inhibitor, which targets several tyrosine kinases receptors (RTK), such as VEGFR2 and VEGFR3, PDGFRβ, fibroblast growth factor receptor 1 (FGFR1), and Flt-3, RET, and c-Kit, all involved in tumor growth progression and neoangiogenesis. Here, FGFR1 is linked to neoplasm.