Fig. 2G–I shows representative tissues of vimentin protein expression in ducts found in sections of biopsies from breast cancer patients, as determined by immunoperoxidase staining. This expression was negative in noninvasive ductal carcinoma and breast epithelial lesions surrounding the primary tumors, ductal and lobular hyperplasia, and microcytes. By contrast, this expression was positive in breast specimens with invasive characteristics, as shown in Fig. 2J–L. Here, VIM is linked to breast cancer.