In a multivariate regression model including age (≥55 years), platelet count (<17 × 104/μl), albumin (<4.4 g/dl), ALT (≥43 IU/l), γ-GTP (≥27 IU/l), AIM (≥1.2 μg/ml), and hyaluronic acid (≥40 ng/ml), advanced hepatic fibrosis was independently associated with ALT, AIM, and hyaluronic acid (Table 4). This evidence concerns the gene CD5L and Hepatic fibrosis.