TARDBP and amyotrophic lateral sclerosis: Only recently, with advanced genomic screening tools, several other genes associated with ALS have been identified including TAR DNA-binding protein (TDP-43), FUS, ALS 2 (ALS2), neurofilament heavy peptide (NEFH; Al-Chalabi et al., 2012) and C9ORF72 (DeJesus-Hernandez et al., 2011; Renton et al., 2011).