CYCS and Alzheimer disease: The quantification of the Western blot showed that the isoflurane treatment (black bar) increased the cytosol levels of cytochrome c as compared to the control condition (white bar) in WT mice neurons (Figure 3E): 140% versus 100%, * P = 0.025; and in AD Tg mice neurons (Figure 3F): 143% versus 100%, ** P = 0.003.