Erythropoietic protoporphyria (EPP) is a disease associated with a diminished activity of ferrochelatase (FECH) (EC.4.99.1.1), the final enzyme of heme biosynthesis that catalyzes the conversion of protoporphyrin (PROTO IX) into heme [1, 2]. This evidence concerns the gene FECH and autosomal erythropoietic protoporphyria.