In a recent review [74] and two proteomic studies [75,76], increasing of low abundant proteins such as IL-8, CD14, SAA, S100A12 and PTX3, were reported in mastitis milk from ewes and cows experimentally infected by E. coli, S. aureus and S. uberis or challenged with LPS, thus corroborating our transcriptional findings. This evidence concerns the gene S100A12 and mastitis.