In a recent review [74] and two proteomic studies [75,76], increasing of low abundant proteins such as IL-8, CD14, SAA, S100A12 and PTX3, were reported in mastitis milk from ewes and cows experimentally infected by E. coli, S. aureus and S. uberis or challenged with LPS, thus corroborating our transcriptional findings. The gene discussed is PTX3; the disease is mastitis.