INS and polycystic ovary syndrome: In ourstudy, we observed that among the estimates of insulinsensitivity, the HOMA-IR was significantlyhigher, whereas the fasting glucose/insulin ratiowas lower in heavy smokers than in other groups.In addition to the fasting insulin levels, the insulinogenicindex and the HOMA-B (all indices ofpancreatic β-cell function) resulted in significantlyhigher value for PCOS smoking patients thanweight matched non-smokers.