Theirresult showed that there was higher serum cortisol andcorticotrophin-releasing hormone (CRH) in infertilewomen than healthy control (3), while the similarstudies suggest that higher level of stress accompanieswith lower level of success in infertility therapy (4-7).Feeling of threat, sexual concern, guilt, hopelessnessand marital problems are related to infertility (8). Here, CRH is linked to Infertility.