In addition, commonprimary conditions are antithrombin III, proteinC, protein S deficiency, as well as the presenceof antiphospholipid antibodies, anticardiolipinantibodies, factor V leiden gene mutation, resistanceto activated protein C, and prothrombinG20210A mutation (3,8). This evidence concerns the gene PROS1 and hyperinsulinemic hypoglycemia, familial, 4.