Thefindings showed that adiponectin decreased cellproliferation in human endometrial cancerous tissuevia adiponectin receptors and the level of AdipoR1 expression was higher than that of AdipoR2 but the level of expression of receptors in canceroustissue did not indicate significant differencecompared to normal non-cancerous tissue (30).The recent research has indicated that expressionof Adipo R1 in breast cancer cells (32) and humanendometrial cancerous tissue (23) is higher thanth at of Adipo R2. This evidence concerns the gene ADIPOR1 and breast cancer.