Based on the current study, ovarian stimulationperformed with hMG in PCOS patients treatedwith a long GnRH agonist protocol results inthe same clinical pregnancy and take baby homerates compared to ovarian stimulation with rFSH.However, for the consideration of other importantfactors such as the need of coasting and safety inparticular, hMG has major advantages over rFSH.This results warrant further evaluation in a largerprospective series. This evidence concerns the gene GNRH1 and polycystic ovary syndrome.