TIMP-2 was positive in all (100%) the individuals with oncocytoma (range, 184–445 ng/ml; mean ± SD, 300±110 ng/ml) and in 15/16 (94%) of the ccRCC patients (range, 52–452 ng/ml; mean ± SD, 248±105 ng/ml). Here, TIMP2 is linked to oncocytic adenoma.