Weir and colleagues reported that plasma galectin-3 levels increased significantly following MI (mean, 46 h after MI) and was positively associated with remodeling parameters in patients with supra-median baseline LV ejection fraction (>49.2 %) but not when LV ejection fraction was ≤49.2 % [125]. The gene discussed is LGALS3; the disease is myocardial infarction.