ID1 and ischemia reperfusion injury: To determine the role of Id proteins in vascular remodeling and repair in the kidney, we examined expression patterns of Id 1 and 3 in normal kidney and following ischemia-reperfusion injury (IRI) and differences in microvascular repair and interstitial fibroblast responses in wild type, Id1−/−, Id3+/− and mice with inducible transgenic endothelial cell Id1 overexpression.