Five non-syndromic RP families presented 4 new (2 missense, one nonsense and one splicing mutation) and 7 reported (5 missense, one nonsense and one splicing mutation) pathogenic alleles in USH2A. In the Usher cohorts, analysis of USH2A rendered 2 new missense and 3 known (one frameshift and 2 missense) mutations. The gene discussed is USH2A; the disease is retinitis pigmentosa 1.