Eliopoulos and Fibbe [35], [38] have reported increasing CD8a+ T-lymphocytes, NK cells, and NKT cell numbers after coinfusion of CD34+ haematopoietic stem cells and allogeneic MSCs in the context of haematopoietic stem cell transplantation, which is contrary to the postulated immunosuppressive effects of MSCs and the related promising expectations of using MSCs in the therapy of GvHD. This evidence concerns the gene CD8A and graft versus host disease.