CRX and Leber congenital amaurosis: Mutations in human CRX (NCBI Reference Sequence: NG_008605.1) have been associated with autosomal dominant forms of the retinal degenerative diseases Retinitis Pigmentosa (adRP), Cone-Rod Dystrophy (adCoRD) and Leber Congenital Amaurosis (adLCA), with different ages of onset and severity [12], [22]–[45].