29, who reported that galectin-7 protein expression increases during tumor progression in hypopharyngeal and laryngeal SCC. However, this research team also reported that the percentage of cells immunopositive for galectin-7 decreased significantly with the loss of histological differentiation in hypopharyngeal SCC 30. Furthermore, tumor progression was associated with a translocation of galectin-7 from the nucleus to the cytoplasm 29. Here, LGALS7 is linked to neoplasm.