In contrast, upon co-culture with HK C. albicans, PBMCs from RA subjects produced significantly lower IL-17A than control PBMCs (mean: 259.2 pg/ml, range: 0 to 798.9 vs. mean: 508.1 pg/ml, range: 34.8 to 925; P = 0.006) (Figure 1A). This evidence concerns the gene IL17A and rheumatoid arthritis.