The data from the Sanger Institute Cancer Genome Project-Catalogue of Somatic Mutations in Cancer revealed the presence of IDH1 mutations in more than 32% of central nervous system tumors, 23% of bone tumors, 8% of biliary tract tumors, 6% of thyroid cancer, and many other tumor types [14] (Figure 3). Here, IDH1 is linked to thyroid gland carcinoma.