To test this, we adoptively transferred naive CD4+ T cells from DO11.10.Rag1−/− and DO11.10.Rag1−/−Cblb−/− mice into WT BALB/c recipients, and then immunized with OVA at 100 μg/ml in alum, which is the dose used to induce asthma. Here, CD4 is linked to asthma.