Gene ontology analysis showed that this cluster was strongly enriched for terms relating to wound healing (Fig. 4c), and arginase-1, Chi3l3, Ear11 and Il4i1 were amongst the most strongly induced genes in this cluster (Fig. 4d) - all well-known markers of alternative macrophage activation, which have recently been shown to be induced during infection with certain strains of Toxoplasma[36]. The gene discussed is IL4I1; the disease is infection.