HGF and prostate neoplasm: In order to determine if Troglitazone can also prevent HGF-induced cell surface-directed lysosome trafficking, DU145 prostate tumor cells were co-treated with 10 μM Troglitazone and 33 ng/μl HGF for 16 hrs, after which lysosomes were visualized by I.F. microscopy using LAMP1 (lysosome-associated membrane protein-1) as a previously established lysosome marker [9].